As part of the investigation into the "Jack the Ripper" affair, Francis J. Tumblety, a quack doctor, is arrested and released on bail. He immediately flees to the United States. Alerted by London, the New York police are on the lookout for Tumblety. Various witnesses confirm his presence in Manhattan and crimes are committed with a modus operandi similar to those in London. The police call upon some of the city's most eminent citizens to help them with their investigation. Is Tumblety really Jack? If not, who is he pretending to be? These are the stakes in "Mr. Jack in New York"