Macroscope features a funky box-shaped device covered with cardboard tokens, and this device comes loaded with two hundred double-sided cards, with each card featuring a black-and-white line drawing. On a turn, a player rolls the two dice, then removes one or two tokens from the box that match the numbers rolled. When you remove a token, you see through a hole in the box that reveals part of the topmost line drawing. If the player wants, they can guess what the drawing represents, after which they pull the card out of the box to see whether they are correct, scoring points based on the number of tokens removed if correct and losing points otherwise. After ten rounds, the player with the most points wins.